prolonged hypercapnea in chronic lung disease

[shivugm33]

Dear all,

Are there any studies looking at long term effects of hypercapnea in chronic lung disease ?
I am looking after a baby (corrected gestational age - term) who is beginning to cycle on CPAP. PCO2 remains around 16 - 19 kpa. However, pH is compensated around 7.31 to 7.32.

regards

Dr. Shankar

[JACK]

Article (http://www3.interscience.wiley.com/journal/88512195/abstract)

[hkhawahur]

From my review to literature the recommendation is not to exceed Pco2 of 55 mm gh ; unless it is a research issue .