skin colour change in staph sepsis?

[selvanr4]

we had 2 newborns prentong with culture proven staph sepsis.
they had colour change to black pigmentation while on drugs.
any strain which causes colour change?

[JACK]

Could it be due to the drug used ? Which antibiotic was used in these cases ?

[selvanr4]

both the babies received inj. amikacin and piperacillin &tazobactum.
they have received platelet transfusions also
selvan

[Stefan Johansson]

Looks like the infant developed a pustular rash.

How about this condition?
"Acute Generalized Exanthematous Pustulosis: A Rare Clinical Entity With Use of Piperacillin/Tazobactam."
http://www.ncbi.nlm.nih.gov/pubmed/19352142

[selvanr4]

i agree to the pustular rash on the foot. But the black colour change on the face, nape of neck are out of blue. i will search again and come back to you with the latest pictures next week when they come back fo review from the primary care practitioner.

[Dukstar]

I saw these slate-like coloration in neonatal chikungunya infection
Was there an epidemic of chikungunya at this period in your setting ?

[JACK]

Was any lotion applied locally ? Any herbal medicines ?

[selvanr4]

we have chikungunya infection as epidemic right now with dengue .
no lotion was applied .
i am posting other photos
selvan.r.
india

[Dukstar]

It seems that the hyperpigmentation interest periorificial sites and lobes of the ears.
You can screen for CHIKV infection (perhaps IgM if too late for RT-PCR), specially if these newborns have been febrile...
Maternal-fetal transmission has been described with febrile mothers during the peripartum period with onset of disease in neonates after some days.
See my publication here :

http://www.ncbi.nlm.nih.gov/pubmed/17721376?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

[selvanr4]

thanks a lot for the information.
indeed i could get more information after seeing your article.
both the babies are well and thriving and now in their homes.
thanks
selvan.r