Meropenem + Metronidazol right or wrong combination ?

[Leonora DEsposito]

I'm looking for an anaerobic coverage in a baby with meropenem.
Found it "incompatible"...in some references. Is this about the inyection site or a drug interaction ? Thanks...Regards.Leonora.;)

[tdifan_2003]

I'm looking for an anaerobic coverage in a baby with meropenem.
Found it "incompatible"...in some references. Is this about the inyection site or a drug interaction ? Thanks...Regards.Leonora.;)

Very wrong. Redundant,
I can't attach the file, but there's a paper from this month (November or December) in Peds ID Journal, looking at appropriatnes of ABx use in the NICU.
Let me know if uou can't get it and I'll e-mail it to you.
Millen

[JACK]

I'm looking for an anaerobic coverage in a baby with meropenem.
Found it "incompatible"...in some references. Is this about the inyection site or a drug interaction ? Thanks...Regards.Leonora.;)

Meropenem itself has excellent anaerobic coverage. So it does not seem rational to use meropenem and metronidazole at the same time
LINK (http://www.expert-reviews.com/doi/pdf/10.1586/14787210.2.1.153)

[tdifan_2003]

I hope the attachment worked ;)

[Leonora DEsposito]

Both articles very useful. Thanks JACK and Millen.
Infection prevention and control is for us a life or death matter.

[JACK]

I hope the attachment worked ;)

Good one !!!

[vijayashankara]

bringing in appropriate usage of antibiotics is a very difficult proposition, particularly when you do not have written accepted protocols; every time there is a prescription, there is always an explanation, however unconvincing it may be.