Congenital Rubella Syndrome

[kpsanghvi]

Hi All

I have a newborn with Congenital Rubella Syndrome (IUGR, Cataract, Small ASD, PDA, Thrombocytopenia, Periventricular Calcifications, Sensorineural deafness, Rubella IgM +ve).

I would like to know how long does the thrombocytopenia last. How do I treat it? (Platelet transfusions v/s IV IgG).

When do I start immunisation?

[Stefan Johansson]

As far as I know, there's only supportive treatment for thromobocytopenia related to congenital rubella, i.e. I would transfuse if platelet levels got critically low (<15-20).

Anyone else with recent experience of congenital rubella?

[kpsanghvi]

Hi Stefan

Thanks for the reply. I have used IV IgG. I shall get back to you once I get the platelet count. (Patient is discharged)
The query of starting immunisation is still unanswered.

[Stefan Johansson]

Did you check immune status of the staff caring for this child?
I understand that infants with congenital rubella excrete large amounts of viruses.

There is a national database (in Swedish unfortunately) on infections during pregnancy, www.infpreg.com.
This info (http://www.medscinet.se/infpreg/specinfo/main.asp?topic=28) on Rubella (in Swedish..) but at the bottom you'll find references which you may find useful.

[kpsanghvi]

Thanks for the info. The infants platelet count is now 68,000/mm3