Stefan Johansson
7th January 2008, 21:42
Leading articles - January 2008
The Leading articles for January 2008 is about postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up.
The article is published in collaboration with the journal Archives of Disease in Childhood (http://www.99nicu.org/exhibition/page1/page1.html).
Permission to publish the abstract has been given by Archives of Disease in Childhood.
* * * * * * * * * * * * * * * * * * *
REVIEW ARTICLE
Postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up (http://fn.bmj.com/cgi/content/full/93/1/F58)
K J Rademaker, L S de Vries, C S P M Uiterwaal, F Groenendaal, D E Grobbee, F van Bel
Department of Neonatology, University Medical Center Utrecht/Wilhelmina Children’s Hospital, Utrecht, The Netherlands
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
ABSTRACT
The benefits versus the risks of postnatal administration of steroids in preterm-born infants are still debatable. This review examines the literature on postnatal hydrocortisone treatment for chronic lung disease (CLD) in preterm-born infants with a particular focus on the effects of such treatment on long-term neurodevelopmental outcomes. Quantitative published evidence does not point to a clear advantage of treatment with hydrocortisone over dexamethasone with regard to the impact on long-term neurological outcomes. However, in the absence of a randomised comparison, a consensus may soon have to be reached on the basis of the best available evidence whether hydrocortisone should replace dexamethasone in the treatment of CLD.
* * * * * * * * * * * * * * * * * * *
You may comment the article directly below or discuss chronic lung disease and neurological outcomes in the forums Pulmonary disorders (http://www.99nicu.org/forum/forumdisplay.php?f=43) and Neurology (http://www.99nicu.org/forum/forumdisplay.php?f=45).
The Leading articles for January 2008 is about postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up.
The article is published in collaboration with the journal Archives of Disease in Childhood (http://www.99nicu.org/exhibition/page1/page1.html).
Permission to publish the abstract has been given by Archives of Disease in Childhood.
* * * * * * * * * * * * * * * * * * *
REVIEW ARTICLE
Postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up (http://fn.bmj.com/cgi/content/full/93/1/F58)
K J Rademaker, L S de Vries, C S P M Uiterwaal, F Groenendaal, D E Grobbee, F van Bel
Department of Neonatology, University Medical Center Utrecht/Wilhelmina Children’s Hospital, Utrecht, The Netherlands
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
ABSTRACT
The benefits versus the risks of postnatal administration of steroids in preterm-born infants are still debatable. This review examines the literature on postnatal hydrocortisone treatment for chronic lung disease (CLD) in preterm-born infants with a particular focus on the effects of such treatment on long-term neurodevelopmental outcomes. Quantitative published evidence does not point to a clear advantage of treatment with hydrocortisone over dexamethasone with regard to the impact on long-term neurological outcomes. However, in the absence of a randomised comparison, a consensus may soon have to be reached on the basis of the best available evidence whether hydrocortisone should replace dexamethasone in the treatment of CLD.
* * * * * * * * * * * * * * * * * * *
You may comment the article directly below or discuss chronic lung disease and neurological outcomes in the forums Pulmonary disorders (http://www.99nicu.org/forum/forumdisplay.php?f=43) and Neurology (http://www.99nicu.org/forum/forumdisplay.php?f=45).